hrp0084p1-77 | Fat | ESPE2015

Evaluation of Adiponectin Concentrations in Obese Children and Its Correlation with Lipid and Carbohydrate Parameters

Ruminska Malgorzata , Majcher Anna , Pyrzak Beata

Aims: The aims of the study was to evaluate the plasma adiponectin levels in obese children depending on children age, gender, stage of puberty and its relationship with lipid and carbohydrate metabolism parameters.Material and method: The study were involved 122 obese children (52 girls, 70 boys), aged 5.3–17.9 years (11.6±3 years), 52 children in prepubertal, and 65 in pubertal period. Obesity was defined using IOTF criteria. The control grou...

hrp0086p2-p949 | Thyroid P2 | ESPE2016

Thyroid Function in Obese Children and Its Correlations with Chosen Atherogenic Risk Factors

Ruminska Malgorzata , Witkowska-Sedek Ewelina , Majcher Anna , Pyrzak Beata

Background: Moderately elevated thyroid-stimulating hormone (TSH) with normal serum concentrations of free thyroxine (fT4), suggesting subclinical hypothyroidism, is the most common hormonal abnormality in obese children. Controversy remains whether thyroid dysfunction related to obesity has an influence on the cardiovascular risk factors.Objective and hypotheses: The aim of the study was to assess correlation between TSH and fT4 and chosen atherogenic r...

hrp0092p1-73 | GH and IGFs | ESPE2019

Influence of Birth Parameters on Growth Response and Metabolic Effects of Growth Hormone (GH) Therapy in GH-deficient Children and Adolescents

Witkowska-Sedek Ewelina , Ruminska Malgorzata , Kucharska Anna M. , Majcher Anna , Pyrzak Beata

Introduction: Growth depends on growth hormone (GH) secretion and on individual sensitivity to its action. The effects of birth parameters on growth and metabolic status are well documented in small-for-gestational-age children, but in children with GH deficiency those associations are not clear. Taking into account that GH-deficient children are not a homogenic group of patients, the importance of an individual approach to GH doses and the assessment of the e...